Media and publications

Protocol registration

The study has been registrered at ClinicalTrials.gov: NCT02999412.

Ethical approval

The study has been ethically approved by the Central Ethical Review Board (Centrala etikprövningsnämnden; CEPN): registration number Ö21-2016. Additional ethical approval for interviews with patients and healthcare professionals was received by the Regional Ethical Review Board in Uppsala: registration number 2016/251/1.

Peer-reviewed publications

- Kempen TGH, Kälvemark A, Gillespie U, Stewart D. "Comprehensive medication reviews by ward-based pharmacists in Swedish hospitals: What does the patient have to say?". J Eval Clin Pract. 2019 Mar 4. doi: 10.1111/jep.13121.

- Kempen TGH, Hedström M, Olsson H, Johansson A, Ottosson S, Al-Sammak Y, Gillespie U. "Assessment tool for hospital admissions related to medications: development and validation in older patients". Int J Clin Pharm. 2018 Dec 26. doi: 10.1007/s11096-018-0768-8.

- Kempen TGH, Bertilsson M, Lindner KJ, Sulku J, Nielsen EI, Högberg A, Vikerfors T, Melhus H, Gillespie U. "Medication Reviews Bridging Healthcare (MedBridge): Study protocol for a pragmatic cluster-randomised crossover trial". Contemp Clin Trials. 2017 Jul 21;61:126-132.

Conference proceedings

- 47th European Symposium on Clinical Pharmacy, Belfast, United Kingdom, 24-26 October 2018. Poster presentation: Kempen TGH, Kälvemark A, Gillespie U, Stewart D. “Comprehensive medication reviews in Swedish hospitals: what does the patient have to say?”.

- The Clinical Pharmacy Congress, London, Great-Britain, 27-28 April 2018. Poster presentation: Cam H, Kempen TGH. "Intervention fidelity within a clinical study on comprehensive medication reviews in hospitalised patients (MedBridge study)".

- 23rd European Association Hospital of Pharmacists Congress, Goteborg, Sweden, 21-23 March 2018. Poster presentation: Sawires M, Kempen TGH, Gillespie U. "A nested qualitative study of medication reviews within a multicentre cluster-randomised crossover trial (MedBridge)".

- 23rd European Association Hospital of Pharmacists Congress, Goteborg, Sweden, 21-23 March 2018. Poster presentation: Al-Sammak Y, Gillespie U, Kempen TGH. "Assessment Tool for Hospital Admissions Related to Medications, 10 questions (ATHARM10): a validation study".

- 46th European Symposium on Clinical Pharmacy, Heidelberg, Germany, 9-11 October 2017. Poster presentation: Cam H, Kempen TGH. "Intervention fidelity within a clinical study on comprehensive medication reviews in hospitalised patients (MedBridge study)".

- 17th International Conference for Integrated Care 2017, Dublin, Ireland, 8-10 May 2017. Poster presentation: Kempen TGH, Bertilsson M, Lindner KJ, Sulku J, Nielsen EI, Högberg A, Vikerfors T, Melhus H, Gillespie U. "Medication Reviews Bridging Healthcare (MedBridge): Study protocol for a pragmatic cluster-randomised crossover trial".

News articles

- "Världsunik studie ska fånga nyttan med klinisk farmaci" – Svensk Farmaci, 22 February 2017 (in Swedish)

- "Bra start för unik studie av klinisk farmaci" – Svensk Farmaci, 27 February 2017 (in Swedish)

- "MEDBRIDGE – världens största randomiserade studie i klinisk farmaci" – Läkemedelsbulletinen, Läkemedelskommittén i Västmanland, November 2017, 18:3;p.4-5 (in Swedish)

Related publications

- Kempen TGH, Gillespie U, Färdborg M, McIntosh J, Mair A, Stewart D. “A case study of the implementation and sustainability of medication reviews in older patients by clinical pharmacists”. Res Social Adm Pharm. 2018 Dec 19. pii: S1551-7411(18)30868-4. doi: 10.1016/j.sapharm.2018.12.006.

- McIntosh J, Alonso A, MacLure K, Stewart D, Kempen T, Mair A, Castel-Branco M, Codina C, Fernandez-Llimos F, Fleming G, Gennimata D, Gillespie U, Harrison C, Illario M, Junius-Walker U, Kampolis CF, Kardas P, Lewek P, Malva J, Menditto E, Scullin C, Wiese B; SIMPATHY Consortium. “A case study of polypharmacy management in nine European countries: Implications for change management and implementation.” PLoS One. 2018 Apr 18;13(4):e0195232. doi: 10.1371/journal.pone.0195232.

- Stewart D, Gibson-Smith K, MacLure K, Mair A, Alonso A, Codina C, Cittadini A, Fernandez-Llimos F, Fleming G, Gennimata D, Gillespie U, Harrison C, Junius-Walker U, Kardas P, Kempen T, Kinnear M, Lewek P, Malva J, McIntosh J, Scullin C, Wiese B. “A modified Delphi study to determine the level of consensus across the European Union on the structures, processes and desired outcomes of the management of polypharmacy in older people”. PLoS One. 2017 Nov 20;12(11):e0188348. doi: 10.1371/journal.pone.0188348.

- Stewart D, Mair A, Wilson M, Kardas P, Lewek P, Alonso A, McIntosh J, MacLure K; SIMPATHY consortium. “Guidance to manage inappropriate polypharmacy in older people: systematic review and future developments”. Expert Opin Drug Saf. 2017 Feb;16(2):203-213. doi: 10.1080/14740338.2017.1265503.

- Alassaad A, Melhus H, Hammarlund-Udenaes M, Bertilsson M, Gillespie U, Sundström J. "A tool for prediction of risk of rehospitalisation and mortality in the hospitalised elderly: secondary analysis of clinical trial data". BMJ Open. 2015 Feb 18;5(2):e007259.

- Alassaad A, Bertilsson M, Gillespie U, Sundström J, Hammarlund-Udenaes M, Melhus H. "The effects of pharmacist intervention on emergency department visits in patients 80 years and older: subgroup analyses by number of prescribed drugs and appropriate prescribing". PLoS One. 2014 Nov 3;9(11):e111797.

- Gillespie U, Alassaad A, Hammarlund-Udenaes M, Mörlin C, Henrohn D, Bertilsson M, Melhus H. "Effects of pharmacists' interventions on appropriateness of prescribing and evaluation of the instruments' (MAI, STOPP and STARTs') ability to predict hospitalization--analyses from a randomized controlled trial". PLoS One. 2013 May 17;8(5):e62401.

- Alassaad A, Gillespie U, Bertilsson M, Melhus H, Hammarlund-Udenaes M. "Prescription and transcription errors in multidose-dispensed medications on discharge from hospital: an observational and interventional study". J Eval Clin Pract. 2013 Feb;19(1):185-91.

- Gillespie U, Mörlin C, Hammarlund-Udenaes M, Hedström M. "Perceived value of ward-based pharmacists from the perspective of physicians and nurses". Int J Clin Pharm. 2012 Feb;34(1):127-35.

- Gillespie U, Alassaad A, Henrohn D, Garmo H, Hammarlund-Udenaes M, Toss H, Kettis-Lindblad A, Melhus H, Mörlin C. "A comprehensive pharmacist intervention to reduce morbidity in patients 80 years or older: a randomized controlled trial". Arch Intern Med. 2009 May 11;169(9):894-900.